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SmartState: An Automated Research Protocol Adherence System

Key features and benefits of SmartState include:

  • Automated management of participant interactions, communications, and data collection, reducing the workload on researchers and preventing errors or inconsistencies.
  • Use of finite state machines to track participant progress and ensure adherence to study protocols, preventing critical steps from being skipped.
  • Integration of a large language model to facilitate natural language interactions with participants, distill conversations into structured data, and automate responses.
  • Provision of a web-based platform for researchers to access participant logs, reports, and messaging utilities, enabling seamless interaction with the underlying system.
  • Increased scalability and efficiency for large studies, making it applicable to many research areas.Detailed auditing capabilities to trace a participant’s exact path through a study, preventing disputes between researchers and participants

Clinical Research projects currently using SmartState:

  • Time-Restricted Eating Intervention in Normal and Cognitively Impaired Postmenopausal Women
  • Time-Restricted Eating and Sleep Intervention in College Students
  • Optimal CT
  • Plant-Based Diet for Diabetes Prevention (PBDDP)

Below is the latest submission to the American Medical Informatics Association (AMIA) Informatics Summit 2025.

https://arxiv.org/pdf/2305.04411